Coenzyme Q10

Coenzyme Q10 is a powerful antioxidant that plays a crucial role in cellular energy production and has been studies for its benefits on sperm health.

1. Sperm Count and Motility: Research demonstrates that 6-months of CoQ10 supplementation improves sperm concentration, motility, and morphology¹. A second open label study demonstrated significant improvement in sperm motility of almost 10%². Other studies found an overall 5-fold increase in sperm counts and 5-fold increase in sperm motility after CoQ10 therapy³. It is important to note that dosage of CoQ10 in the majority of strong studies were between 200-300 mg.
2. Antioxidant activity & DNA Integrity: Research evaluating CoQ10 200 mg daily for 3 months significantly reduced sperm DNA damage levels as well as improved concentration and motility⁴.

References:

1. Safarinejad MR, Safarinejad S, Shafiei N, Safarinejad S. Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study. J Urol. 2012;188(2):526-531. doi:10.1016/j.juro.2012.03.131
2. Balercia G, Mosca F, Mantero F, et al. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril. 2004;81(1):93-98. doi:10.1016/j.fertnstert.2003.05.009
3. Lafuente R, González-Comadrán M, Solà I, et al. Coenzyme Q10 and male infertility: a meta-analysis. J Assist Reprod Genet. 2013;30(9):1147-1156. doi:10.1007/s10815-013-0047-5
4. Alahmar AT, Calogero AE, Sengupta P, Dutta S. Coenzyme Q10 Improves Sperm Parameters, Oxidative Stress Markers and Sperm DNA Fragmentation in Infertile Patients with Idiopathic Oligoasthenozoospermia. World J Mens Health. 2021;39(2):346-351. doi:10.5534/wjmh.190145